CETSA® and Alpha

CETSA® in combination with Alpha detection technology can efficiently assess target engagement in live cells. The Alpha technology is sensitive, and the workflow is highly suitable for automation and high throughput screening purposes.

We have fully validated a set of protein target kits available as Alpha CETSA® kits. We have also pre-validated over 40 total AlphaLISA® SureFire® Ultra protein kit targets proving that they are amenable with CETSA®. These protein targets are now available as CETSA® ble kits. See table below with available AlphaCETSA® and CETSA®ble kit targets.

These kits can be purchased direct from PerkinElmer and their use with CETSA® is permitted under a license from Pelago Bioscience.

Licences

Single Target License: Lifetime license agreement for either PerkinElmer kits or custom assay development services from Pelago. Available for a defined target for a single fixed fee. Contact Pelago Bioscience for details.

Single Kit Agreement:  Pay-as-you-go option. Intended for customers purchasing PerkinElmer kits for use with CETSA®.

PerkinElmer will only ship kits to a customer once Pelago Bioscience confirm that a subscription is in place. Contact us to learn more.

Speak to our experts

Learn how Pelago Bioscience can provide unique insights to your project by talking to one of our Drug Discovery experts.