Fine-tune
your leads
We show what your compounds really do inside cells and reveal real-world target engagement and off-target effects, so you can push the best molecules forward with clarity.
Potency Ranking
Prioritize compounds to lower the risk of failures in later development stages.
Selectivity Profiling
Reveal off-target interactions with unbiased, proteome-wide profiling.
Target Identification and Deconvolution
See compound-target interactions in conditions that reflect actual cellular environments.
Mechanism of Action
Gain a clear understanding of compound activity across the proteome in biologically relevant conditions.
Translational Studies
Confirm target engagement across cell lines, animal tissues, and human-derived systems for reliable translational insights.

Why CETSA?
What makes CETSA different?
See CETSA in action
Read our case stories.
Unbiased Selectivity Profiling with CETSA® and Mass Spectrometry
Unbiased Selectivity Profiling: Revealing True Compound Specificity and Off-Target Interactions…
Employing CETSA® in Primary Screening for p53 Binders
CETSA p53 Screening: Uncovering Potential Cancer Therapeutics Targeting p53, a key tumor suppre…
Enhancing Degrader Research with CETSA®
Unlocking New Insights into Targeted Protein Degradation with CETSA: Revealing Both Target Enga…