Fine-tune
your leads
We show what your compounds really do inside cells and reveal real-world target engagement and off-target effects, so you can push the best molecules forward with clarity.
Potency Ranking
Prioritize compounds to lower the risk of failures in later development stages.
Selectivity Profiling
Reveal off-target interactions with unbiased, proteome-wide profiling.
Target Identification and Deconvolution
See compound-target interactions in conditions that reflect actual cellular environments.
Mechanism of Action
Gain a clear understanding of compound activity across the proteome in biologically relevant conditions.
Translational Studies
Confirm target engagement across cell lines, animal tissues, and human-derived systems for reliable translational insights.
Why CETSA?
What makes CETSA different?
See CETSA in action
Read our case stories.
Selectivity Profiling: Unbiased Analysis of Compound Selectivity in Drug Discovery
Join us for an in-depth webinar exploring how CETSA® Selectivity Profiling empowers smarter decision-making in drug discovery. Drew Nager will share how Pfizer Oncology leverages Pelago Bioscience’s C…
Novel Applications of the Cellular Thermal Shift Assay (CETSA) Provide New Insights for Drug Discovery
Join AbbVie scientists Shitalben Patel and Jami R. Erickson as they showcase their innovative advancements, transforming CETSA® into a high-throughput flow-based platform and introducing new whole blo…
Unbiased Selectivity Profiling: with CETSA® and Mass Spectrometry
Unbiased Selectivity Profiling: Revealing True Compound Specificity and Off-Target Interactions CETSA mass spectrometry profiling enables unbiased analysis of compound selectivity in drug discovery—he…