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Drug Discovery Trends 2025

The Top 5 Drug Discovery Trends Defining 2025: What They Mean for the Future of Innovation

Introduction: Navigating a Transformative Year in Drug Discovery  Drug Discovery Tren...

mutant p53 CETSA thermal stability analysis

Cracking the Code of Mutant p53: A CETSA®-Powered Investigation at AACR 2025 

Our mutant p53 CETSA AACR study reveals novel findings in cancer biology. The tumor suppre...

high quality hits in drug discovery with CETSA

What Makes a High-Quality Hit in Early Drug Discovery? 

Why enhancing confidence in primary screening is critical to translational success—and how...

CETSA selectivity profiling for drug discovery

What Is Unbiased Selectivity Profiling? A CETSA®-Based Approach to Drug Discovery 

CETSA selectivity profiling is crucial in pursuing safer and more efficacious therapeutics...

Proteome-wide CETSA® profiling in early-stage drug discovery

Accelerating Drug Discovery with Proteome-Wide CETSA® Profiling: Why Timing Is Everything 

At Pelago Bioscience, we work with drug discovery teams to optimize their approach to targ...

Why Drug Candidates Fail During Development: The Challenges of Target Engagement

Importance of Target Engagement in Drug Discovery Despite billions invested in drug develo...

Using CETSA® to Measure Target Engagement in Whole Blood

Validating target engagement is a crucial step in drug development, helping us understand ...

Are Your Degraders Delivering on Their Promise? 

Biologically Relevant Insights for Protein Degraders with CETSA®  Targeted protein de...

Is Your Hit on Target?

How to Confidently Validate Drug Discovery Hits A blog post High-throughput screening...