Preclinical Studies in New Drug Development
Move forward with confidence
Our cellular insights guide smarter preclinical decisions — helping you validate mechanisms, assess selectivity, and choose the right candidates to advance.
In-Vivo Target Engagement
Assess efficacy and safety before entering human trials.
Biomarker Discovery
Improve clinical success rates, treatment strategies, and contribute to better patient survival outcomes.
Translational Studies
Confirm target engagement across cell lines, animal tissues, and human-derived systems for reliable translational insights.
Why CETSA?
What makes CETSA different?
See CETSA in action
Explore our case stories.
Unlocking Challenging Targets with CETSA® Across Drug Discovery
Drug discovery increasingly focuses on targets that are difficult to address using traditional approaches. CETSA® enables direct measurement of target engagement in intact cells and complex biological …
Engaged but not degraded
Target engagement profiling of degrader compounds with CETSA CETSA® (Cellular Thermal Shift Assay) is a label-free method for studying small molecule-protein interactions and is especially useful in ta…
On Target Driven Efficacy Assessment of CDK2 Inhibitors in the Right Biological Context
Target Engagement and Selectivity Profiling in K562 and MCF7 Cells CETSA® is a label-free method for assessing target engagement of small molecule-protein interactions. Target engagement determination …