Application Notes
Hit Discovery Process – Is Your Hit on Target?
Validate Early with CETSA® Accelerate hit confirmation and lead optimization with CETSA® from Pelago Bioscience. This application note highlights how CETSA enhances small-molecule drug discovery...
Drug Mechanisms – The Power of Proteome-wide CETSA®
Uncover Drug Mechanisms with Confidence Unlock deeper insights into drug mechanisms with proteome-wide CETSA® from Pelago Bioscience. This application note reveals how CETSA enables unbiased com...
Is Your Compound Actually Therapeutic?
Translatable Insights with CETSA® Translatable Insights with CETSA® on CDK4 and RIPK1 inhibitors, showcasing CETSA’s ability to track engagement from in vitro. Ensure your drug candidate’s ...
Target Engagement with CETSA® – No Target, No Therapy
Direct Insights into Target Engagement with CETSA® Discover how potency ranking with CETSA helps you rank and prioritize drug candidates early in the discovery process. This application note reveals h...
Have you Secured your Clinical Target Engagement Assay?
Harness CETSA® for Target Engagement in Whole Blood Validate target engagement with CETSA to link your drug’s mechanism of action to clinical outcomes. This application note highlights how CETSA’s mat...
Protein Degradation – Are Your Degraders Delivering?
Uncover Mechanisms with CETSA® This application note explores how CETSA reveals target specificity and mechanisms of action, helping optimize degrader molecules for clinical success. Learn from ...