Lead Generation In Drug Discovery
Turn promising hits
into proven leads.
We help you see how compounds engage their targets in real cells – so you can focus on molecules that truly work.
Primary Screen
Speed up your drug discovery process with efficient, high-throughput screening.
Hit Confirmation
Refine the compound design and prioritize the strongest candidates
Potency Ranking
Prioritize compounds to lower the risk of failures in later development stages.
Selectivity Profiling
Reveal off-target interactions missed by conventional panels with unbiased, proteome-wide profiling
Why CETSA?
What makes CETSA different?
See CETSA in action
Read our case stories.
Unlocking Challenging Targets with CETSA® Across Drug Discovery
Drug discovery increasingly focuses on targets that are difficult to address using traditional approaches. CETSA® enables direct measurement of target engagement in intact cells and complex biological …
Engaged but not degraded
Target engagement profiling of degrader compounds with CETSA CETSA® (Cellular Thermal Shift Assay) is a label-free method for studying small molecule-protein interactions and is especially useful in ta…
On Target Driven Efficacy Assessment of CDK2 Inhibitors in the Right Biological Context
Target Engagement and Selectivity Profiling in K562 and MCF7 Cells CETSA® is a label-free method for assessing target engagement of small molecule-protein interactions. Target engagement determination …