Oxford Global Discovery Europe 2024

We are thrilled to share that we will be showcasing our high-throughput screening services at Oxford Global Discovery Europe 2024 in Basel! Join us at the Congress Center Basel to explore how our offerings can support your Drug Discovery journey. We look forward to seeing you there!

    • Visit us at Exhibition Booth 9

    • Attend our 20-minute presentation

    • Meet our team of experts

    • Review our Poster

Presentation Abstract

Many therapeutical relevant drug targets remain undrugged because we lack tools to prosecute them. Through a number of use cases stretching from Target Identification to validation of Lead Series we illustrate how applications of the CETSA® technology opens up novel target space. 

Poster Presentation

  • Title – High Throughput Screening (HTS) with CETSA®: Employing Target Engagement Technology in Primary Screening for p53 Binders

  • Abstract

    High throughput Cellular Thermal Shift Assays (CETSA®) are increasingly adopted earlier in the drug discovery pipeline due to rapid development times and the capability to generate primary hit material for challenging targets. Targets such as p53 can be considered challenging or ‘undruggable’ for a multitude of reasons such as lack of tools, assays, lack of enzyme activity or cellular localization. With CETSA HT screening, challenging targets are prosecuted in their native environment without any modification. Here, a HTS using commercially available screening libraries with subsequent follow-up yielding hit-matter and orthogonal activity data confirming the effect on p53 activity.


We are delighted to extend an invitation for you to join us as our guest at the upcoming Oxford Global Discovery Europe 2024, taking place from May 22 to 23 at the Congress Center Basel.

We are offering three complimentary guest passes on a first-come, first-served basis.

Simply fill out the form, and we will provide you with instructions on how to redeem your full conference pass!