Pelago Bioscience is a Drug Discovery Research Partner supporting preclinical and clinical drug discovery and development. The core of our service is the patented Cellular Thermal Shift Assay (CETSA®) and complementary functional and proteomics assays.

CETSA, unlike other solutions on the market today, allows the assessment and quantification of target engagement under physiological conditions – without the need to modify the compound or protein.

Webinar Series

We frequently organize webinars where we share the latest CETSA technology updates, along with project updates from our clients. These webinars are hosted by both Pelago and industry experts, who possess years of experience in their respective fields.


We hope you find our webinar recordings listed below helpful and informative. If you have any questions or feedback, please feel free to reach out to us.

In this webinar, you will find the details of the project where CETSA Explore was leveraged to study the biological mechanism of the fungal polyketide lactone Brefeldin A (BFA) in human THP-1 cells.

In this webinar, you will learn how Pelago Bioscience can support the early stages of hit identification and validation in a high throughput manner with CETSA Navigate HT and how CETSA Explore provides a proteome-wide analysis of the effects of the PROTACs® to assess their selectivity and with potential to elucidate the MoA.

In this webinar, you will find a presentation of various applications of CETSA® Explore, highlighting how this assay can assist at different stages of drug discovery. CETSA Explore – an unbiased proteome-wide technology for target ID and compound profiling.

In this webinar, you will find case studies where Alpha CETSA has been applied to support lead generation across a broad range of AstraZeneca drug discovery projects.

CETSA is a powerful technology measuring target engagement in live cells, and can be applied to quantify binding to endogenously expressed proteins within disease-relevant cell backgrounds.

Here we present some of the latest results and learnings from the CETSA Explore based Target Engagement Atlas (TEA). In this initiative we have used compressed CETSA Explore to map cellular responses to hundreds of well-known drugs and probes.

You can watch more video content and learn more how we can help you accelerate your drug discovery journey on our YouTube channel.

Learn more about how the CETSA® technology can be applied and the value it provides in different stages of the drug discovery and development process.

Speak to our experts

Learn how CETSA® can enable your project by talking to one of our Drug Discovery experts.